Washington University >> School of Medicine >>
  
Left Header Image Right Header Image Right Header Image Right Header Image
Skip Navigation Links
News
Faculty
Specialties
Research
 in 
 
Faculty Bio

 

Name:                                   Francis Sessions Cole, III
 
E-mail:                                   cole@kids.wustl.edu
Phone:                                  (314) 454 4826
Fax:                                      (314) 454 4633
Campus Box:                         8116
Title:                                      Park J. White Professor of Pediatrics
Pediatric Units:                       Newborn Medicine
                                             Pathobiology Research Unit
                                               
U.S. Mail:                              Washington University School of Medicine
                                             Campus Box 8116
                                             660 S. Euclid Ave.
                                             St. Louis, MO  63110
 
 
Appointments                    
 
Park J. White, M.D., Professor of Pediatrics, Washington University School of Medicine
Assistant Vice Chancellor for Children's Health
Vice Chairman, Department of Pediatrics
Director, Division of Newborn Medicine
Chief Medical Officer, St. Louis Children's Hospital
 
Affiliations                           
 
St. Louis Children’s Hospital; Barnes-Jewish Hospital
Education
1969              BA, Amherst College, Amherst, Massachusetts
1973              MD, Yale University School of Medicine, New Haven
Training
1973-1974    Internship, Children’s Hospital Medical Center
1976-1978    Residency, Children's Hospital Medical Center
1978-1981    Research Fellow in Neonatology and Cell Biology, the Joint  Program in Neonatology, Brigham and Women's Hospital, Boston, Massachusetts
Licensure and Board Certification
1975     Massachusetts
1986     Missouri 
1983     American Board of Neonatal-Perinatal Medicine
1980     American Board of Pediatrics
1973     National Board of Medical Examiners
Honors
Memberships                     
 
American Academy of Pediatrics (Neonatal-Perinatal Section)
American Association of Immunologists
American Federation for Clinical Research
American Pediatric Society
American Society for Clinical Investigation
Perinatal Research Society
Society for Pediatric Research
 
Honors         
 
1994               Invited plenary session speaker, 14th European Congress of Perinatal Medicine, Helsinki, Finland
1997               FDR Leadership Award from the March of Dimes (co-winner with Senator Christopher Bond, Senior Senator from Missouri)
1998               Named the Park J. White, M.D., Professor of Pediatrics
2000               Cartíer First Aide Award, St. Louis Effort For AIDS
2003               Washington University Nominee for the Pfizer Humanism in Medicine Award
2004               Distinguished Service Teaching Award, Washington University School of Medicine, Class of 2007
 
 Areas of Clinical Interest/Research                              
Genetic regulation of neonatal pulmonary surfactant deficiency has been suggested by studies of gender, genetic linkage, recurrent familial cases, targeted gene ablation in murine lineages, and by racial disparity in risk of neonatal respiratory distress syndrome. Successful fetal-neonatal pulmonary transition requires production of the pulmonary surfactant, a phospholipid-protein film that lines alveoli and maintains alveolar patency at end expiration. Our goal is to understand the genetic mechanisms that disrupt pulmonary surfactant metabolism and cause neonatal respiratory distress syndrome...

 

Selected Publications

 

1.      Hamvas A, Wegner DJ, Carlson CS, Bergmann KR, Trusgnich MA, Fulton L, Kasai Y, An P, Mardis ER, Wilson RK, Cole FS. Comprehensive genetic variant discovery in the surfactant protein B gene. Pediatr Res 2007; 62:170-175.
 
2.      Saugstad OD, Hansen TWR, Ronnestad A, Nakstad B, Tollofsrud TA, Reinholt F, Hamvas A, Cole FS, Dean M, Wert SE, Whitsett JA, Nogee LM. Novel mutations in the gene encoding ATP binding cassette protein member A3 (ABCA3) resulting in fatal neonatal lung disease. Acta Paediatr 2007; 96:185-190.
 
3.      Garmany TH, Wambach JA, Heins HB, Watkins-Torry JM, Wegner DJ, Bennet K, An P, Land G, Saugstad OD, Henderson H, Nogee LM, Cole FS, Hamvas A. Population and disease-based prevalence of the common mutations associated with surfactant deficiency. Pediatr Res 2008; 63:645-649.
 
4.      McBee AD, Wegner DJ, Carlson CS, Wambach JA, Yang P, Heins HB, Saugstad OD, Trusgnich MA, Watkins-Torry J, Nogee LM, Henderson H, Cole FS, Hamvas A. Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene. Pediatr Pulmon 2008; 43:443-450.
 
5.      Hamvas A, Heins HB, Guttentag SH, Wegner DJ, Trusgnich MA, Bennet KW, Yang P, Carlson CS, An P, Cole FS. Developmental and genetic regulation of surfactant protein-B in vivo. Neonatol 2008; in press.

 

 
dna
 
| Terms Of Use | Privacy Statement | Copyright 2008 by Washington University in St. Louis, School of Medicine | |